CSF Rhinorrhoea

CSF Rhinorrhoea

  • Leakage of CSF into the nose
  • May or may not be blood stained 
  • Trauma   
    • Accidental or surgical
    • Surgical trauma
      • Endoscopic sinus surgery
      • Trans-sphenoidal hypophysectomy
      • Nasal polypectomy
      • Skull base surgery
  • Inflammation
    • Mucoceles of sinuses
    • Sinonasal polyposis
    • Fungal infection of sinuses
    • Osteomyelitis
  • Neoplasms
  • Congenital lesions
    • Meningocele
    • Meningoencephaloceles
  • Idiopathic
  • History of clear watery discharge from the nose on bending the head or straining
  • RESERVOIR SIGN: discharge from nose seen increased as patient rises in the morning as the fluid collected in the sinus empties into the nose
  • Nasal endoscopy can help to localize CSF leak in some cases.​​​​​
  • Nasal secretions can be sniffed back while CSF can’t be sniffed back 
  • Handerkerchief doesn’t stiffen with CSF secretion ,but stiffens with nasal discharge as it is mucoid
  • Double target sign: CSF fluid mixed with blood when dropped on a filter paper shows a central red dot surrounded by a lighter halo
  • Laboratory test:  presence of Beta-2 transferrin or beta trace proteins (proteins found in csf)
  • High-resolution CT scan
  • MRI                                   
  • Intrathecal fluorescein study          
  • CT cisternogram

6th edition : Diseases of ENT & HN surgery

PL Dhingra, Shruti Dhingra

Page no. 163-165

  • Conservative measures
    • Bed rest
    • Elevating the head of the bed
    • Stool softeners
    • avoidance of nose blowing, sneezing and straining  
  • Prophylactic antibiotics can be used to prevent meningitis.
  • Acetazolamide decreases CSF formation.
  • Neurosurgical intracranial approach
  • Extradural approaches
  • Transnasal endoscopic approach

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